Bus ticket from Istanbul to Safranbolu, There are buses from istanbul to Safranbolu at 09:00 am, 11:30 am, 16:30 pm, 22:30 pm and 23:30 pm and takes about 7 hours from istanbul to Safranbolu by bus.

Bus ticket from Istanbul to Pamukkale, There are overnight buses from istanbul to denizli everyday. the destination is very busy destination for the bus travel to Pamukkale. Bus ride takes about 12 hours. Pamukkale bus company and metro bus company has travel link to Pamukkale from Istanbul and buses go to Denizli then you need to change minibus to Pamukkale about 30 min drive.